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applying stem cells to ask interesting questions
We are each unique, comprised of distinct genetic, epigenetic and environmental risk factors that predispose us to some diseases and confer resilience to others. As expanding genetic studies increasingly demonstrate that both rare variants of large effect and common variants of small effect contribute to a variety of neuropsychiatric disorders, it becomes increasingly critical that we unravel how these risk factors interact within and between the diverse cell types populating the brain.
the Brennand laboratory combines expertise in genetics, neuroscience and stem cells, in order to identify the mechanisms that underlie brain disease. Our focus lies in resolving the convergence of, and complex interplay between, the many risk variants linked to disease, towards the goal of facilitating the clinical translation of genetic findings
mission
unravel the mysteries of the human genome in a collaborative, inclusive, and supportive research training environment
research
our lab seeks to decode highly complex genetic insights into medically actionable information, better connecting the expanding list of genetic loci associated with human disease to pathophysiology
mentoring
take advice and support from everyone willing to provide it. Soon, it will fall on you to help others.